Atopic dermatitis: epidemiology and pathogenesis update.

Update on Epidemiology, Diagnosis, and Disease Course of Atopic Dermatitis Review of Critical Issues in the Pathogenesis of Atopic Dermatitis Assessing the New and Emerging Treatments for Atopic Dermatitis The Changing Paradigm of Atopic Dermatitis Therapy

Pathogenesis of Atopic Dermatitis: Current Paradigm

Atopic dermatitis (AD) is characterized by skin inflammation, barrier dysfunction and chronic pruritus. In this review, recent advances in the pathogenesis of AD are summarized. Clinical efficacy of the anti-IL-4 receptor antibody dupilumab implies that type 2 cytokines IL-4 and IL-13 have pivotal roles in atopic inflammation. The expression of IL-4 and IL-13 as well as type 2 chemokines such a...

Behavioral characteristics in 3-12 month-old infants with Atopic Dermatitis: A case-control study

Background and aim: Atopic dermatitis (AD) is a chronic disorder that is most common in early childhood. Both immunological and psychological factors are important in AD pathogenesis and should therefore be taken into account. The aim of this study was to compare behavioral characteristics of 30 infants (3-12 month-old) with AD with 40 controls.Materials and Methods: Th...

[Review and update of current understanding of childhood atopic dermatitis].

Although childhood atopic dermatitis is reported throughout the world, it has become a health priority in developed countries, where its prevalence is particularly high. Despite extensive study for many years, various aspects of the disease are still subject to debate. This review will discuss the main studies published on the topic and update certain concepts such as the terminology used (the ...

Correlation of total serum IgE and density of house dust mites with severity of Atopic Dermatitis

Background and aim: Atopic dermatitis (AD) is a chronic relapsing skin disease that commonly begins during infancy and early childhood. Research studies refers to a relationship between exacerbation of atopic dermatitis and exposure to house dust mite (HDM), but the role of HDM in the pathogenesis of AD is controversial. The objecitve of this study was to assess the correlation of density...